ABSTRACT
Objective: To investigate self-reported post-vaccination adverse events for COVID-19 vaccines among medical students in Bangladesh. Design and Methods: A cross-sectional study was conducted using an online questionnaire for Bangladeshi medical students (n = 3,545). Students who received at least one dose of COVID-19 vaccine were included. The study was carried out from October 2021 to January 2022 in 75 public and private medical colleges. Result(s): The majority of respondents were female (60.6%) and third-year (26.5%) students. >11% had tested positive for COVID-19 infection, and 97.6% of respondents (n = 3,461) received both first and second doses of COVID-19 vaccination. Most students (79.1%) received Sinopharm and 11.2% got AstraZeneca. More than two-thirds (67.9%) indicated that COVID-19 vaccines are safe in the long term. 54.8% of respondents (n = 1,842) reported one or more adverse events. Pain at injection site (78.2%), fever (49.3%), tiredness and fatigue (46.8%), headache (41.1%), generalized body ache (21.4%), over sleepiness/laziness (18.4%) and myalgia (17.5%) were the most commonly reported adverse events. 47.4% of respondents characterised adverse events as "mild". Majorities experienced symptoms within 12 hours of vaccination (68%) and for 1-3 days (56.8%). More than two-thirds (66.2%) of respondents had rest at home, and almost one-third (31.8%) took painkillers. Thirty-nine respondents visited physicians, mainly due to high fever, severe body ache, and severe headache, but there was no need for hospitalization. Conclusion(s): The majority of students reported adverse events, but symptoms were mild and of short duration. Further multi-centre studies with larger cohorts are required to monitor vaccine safety and strengthen public confidence in vaccines.